Neonatal Cushing Syndrome

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Cushing ' S Syndrome

In 1932 Harvey Cushing described a number of patients presenting a similar clinical picture which he had collected from the literature, and he added two more from his own records. The presence of minute adenomata of basophil cells in the anterior lobe of the pituitary gland was demonstrated at autopsy on some of them and Cushing regarded these as the causative lesions and called the syndrome 'p...

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An infant with Cushing syndrome

Case Presentation An 8 month-old boy was referred to the endocrinology clinic for concerns of growth failure since 3 months of age. He was born full term with a birth weight of 2.67kg and a length of 45cm. His parents noticed that he was not growing well from 3 months of age. However, his weight gain remained more than satisfactory and he gained 700g in the past month. This infant was otherwise...

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Endogenous Cushing syndrome (CS) is caused by excess adrenal glucocorticoid secretion that is adrenocorticotropin (ACTH)-dependent or independent; ACTH-independent adrenocortical causes of CS account for up to 20% of CS in adults, and 15% in children over age 7 years. In younger children, ACTH-independent CS may account for as many as half of the CS cases. In both adults and children, adrenocor...

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ژورنال

عنوان ژورنال: Clinics in Perinatology

سال: 2018

ISSN: 0095-5108

DOI: 10.1016/j.clp.2017.10.002